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KMID : 0614620070500060402
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Korean Journal of Gastroenterology
2007 Volume.50 No. 6 p.402 ~ p.406
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A Case of Sclerosing Cholangitis Showing Response to Prednisolone
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Shin Yo-Sig
Jang Yong-Seok
Kang Min-Kyoung
Jang Byoung-Kuk
Park Kyung-Sik
Hwang Jae-Seok
Kwon Jung-Hyuk
Kang Yu-Na
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Abstract
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Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease characterized by progressive fibrosis and destruction of intra- and extrahepatic bile ducts resulting in hepatic failure and death. Only the liver transplantation is the possible treatment for patients to survive. There has been a few reports that steroid is an effective treatment in autoimmune variant sclerosing cholangitis, which is thought to be a familial diseases with different etiology, and steroid responsive biliary strictures be named as immunoglobulin G4 (IgG4)-associated cholangitis (IAC). There is no reliable data regarding effective steroid treatment in autoimmue variant sclerosing cholangitis in Korea. We report a case of 32-year-old male with sclerosing cholangitis, who was diagnosed by endoscopic retrograde cholangiopancreatography (ERCP) and liver biopsy, showing favorable response to prednisolone therapy. (Korean J Gastroenterol 2007;50:402-406)
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KEYWORD
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Sclerosing cholangitis, Immunoglobulin G4 associated cholangitis, Prednisolone
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